Hope it is obvious to everyone by now, we are headed to a situation where everyone is repeatedly infected by Omicron or whatever the variant du jour is, and we will keep reporting endless numbers of cases as long as we keep testing the way we have been. STOP TESTING. STOP REPORTING. Almost no one will have any serious illness. Cases are supposedly spiking in Minnesota, but hosp and ICU use is down. Cities are putting mask mandates back on, this is all crazy, that is plain and simple what it is. An absolute failure of leadership.
And something very goofy is going on with DOH data. The testing numbers continue to be weird and now we are seeing both regular and ICU admissions dropping, but length of stay increasing? Makes no sense.
Crapload of research today. The morons who run New Zealand quarantine everyone all the time, especially if they come from overseas. And they are mystified because even in their quarantine facility they had an outbreak. They said, oh, there must be airborne transmission. Dooooh. Our epidemic responses are stupid because our experts turn out to be stupid. (CDC Article)
Another study on child hospitalizations supposedly for CV-19 finds that basically no healthy children are hospitalized and finds a very small proportion of children get hospitalized. Buried is the critical piece of data, 44% of these pediatric admissions were not primarily for CV-19. Nonetheless the idiot authors say the results support vaccinating children. I have completely lost my patience with morons who are incapable of the simplest risk/benefit asessment. (Medrxiv Paper)
Sigh, this will feed the conspiracy theorists, but Omicron is one interesting variant. It appears to have an earliest common ancestor of around October 2021, and the most common genomes in a 5 million genomes database are from May and June of 2020, but the number of sequence differences suggests separation of Omicron long ago. My guess is that Omicron, as shown by another study, has better access to animal reservoirs, and was around but somehow didn’t come back into humans until recently. (Medrxiv Paper)
This study from Qatar looked at reinfection risks. It found that prior infection was highly effective against prior variants but reduced by about a third in regard to Omicron. However, protection against hosp and death was high and was equally high against Omicron. (Medrxiv Paper)
Another study finds that T cell responses from infection, vaccination or vax and infection remain strong against Omicron and are boosted by, well, a booster. A small subset of individuals had reduced reactivity. And once more, buried is that prior infection induces both a stronger and more varied T cell response than does vax. (Medrxiv Paper)
Going to rip through some vax effectiveness studies. This study looked at hosps, comparing vaxed and unvaxed patients. The vaxed were also boosted. The vaxed were older and had a higher background risk of serious illness, but still had a lower rates for hospitalization and had a lower need for intensive services when hospitalized. (Medrxiv Paper)
Mixing vaccine types appears to produce stronger T and B cell responses. Prior infection and vaccination produced similar results. (Medrxiv Paper)
And just as with adults, this study from Israel shows a relatively quick lessening of effectiveness against infection in vaxed adolescents. (Medrxiv Paper)
For the 800th time, vaccine effectiveness against infection wanes after a few months. A longer time interval between doses provided greater protection. Mixing vaccine types provided better protection as well. (Medrxiv Paper)
Another one on protection against Omicron. According to this study vaccine protection against Omicron infection was greatly reduced, and while also reduced, the combination of prior infection and vax was far superior to vax alone. (Medrxiv Paper)